From Diablo Wiki
There are three things called Sanctuary in Diablo:
- - The name of the physical realm of man in the Diablo Universe. It is not the only realm, but it is the world in which the Diablo games take place.
- Sanctuary (skill) - An Offensive Aura providing Paladins substantial damage bonus, as well as working to push back and constantly deal holy damage to all Undead in range.
- Sanctuary (runeword) - A shield runeword providing some great defensive bonuses.