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→But theres these really nasty Tomb-Vipers down there that kill my gosu character really fast!!!: blockuqote typo
Because of the way Viper Poison clouds are calculated, having integer DR can drastically improve your living chances. Effectively, the poison cloud is some minor poison damage with the monster's main attack tacked onto it (I think this is similar to the effect found on the Countess Firewalls, actually). Every frame, this gets applied, so the 50-100 physical damage reduced in half will quickly knock down even the most resiliant players with 50% DR.
On the build, it means carrying around some (fairly) nonstandard gear. A maxed PDR/MDR build with marginal resists can tank everything (except poison damage) with great success. Pure kickers will take great advantage from this since sufficient CB can be found from just your weapon and boots. More is better, but this can work well also. Poison damage is the only thing you'll have to work with.</blockuqoteblockquote>
Suffice to say, they are a minor irritation, nothing more.