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From Diablo Wiki
→Sacrifice
* To offset the damage to self, life leech equipment can come in very handy.
* It's possible to kill yourself with Sacrifice, leading to the amusing "Paladin was slain by Paladin." death message in game.
The game will recognize this as PvP, which will nullify experience loss in hell and nightmare difficulties.
* Damage overruns: the key difficulty in using this skill is that you only leech back life based on the monster's hit points, but you lose health based on the damage done.
** Example: if you have 10% life leech and do 500 damage to a monster with 100 hit points, you'll leech back 10 hit points, but lose 8% of 500 = 40.