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From Diablo Wiki
→Sacrifice
* To offset the damage to self, life leech equipment can come in very handy.
* It's possible to kill yourself with Sacrifice, leading to the amusing "Paladin was slain by Paladin." death message in game.
** The game will recognize this as [[PvP]], which will nullify nullifies experience loss in [[hell]] and [[nightmare]] difficulties.
* Damage overruns: the key difficulty in using this skill is that you only leech back life based on the monster's hit points, but you lose health based on the damage done.
** Example: if you have 10% life leech and do 500 damage to a monster with 100 hit points, you'll leech back 10 hit points, but lose 8% of 500 = 40.