Io

If you look at the list of all runes, you can find out the cube recipes to create a rune of one level higher than Io. Here are the Io attributes:

Rank: (r16)
Weapon: +10 Vitality
Armor/Helm/Shield: +10 Vitality
Ilvl/Clvl Required: 35

The Right Runes

Look at the rune list for information on how to get the right runes. For weapons you'll want to find the best type of weapon possible, since that's what the bonus damage is based on. Same with Armor if you are after Defense and shields for blocking percentage. If defense isn't important, look for an item that looks good, has low requirements, and for armor and shields, is not going to slow your running speed.

To Make a RuneWord

1. Items used for RuneWords must be gray text items, normal, exceptional, or Elite. Low Quality, Superior, and Ethereal can be used, but you can not use magical, Rare, Set, Crafted, or Unique items, even if they have the correct number of sockets.
2. The item must be of the correct type.
3. The item must have exactly the correct number of sockets (no more).
4. You must socket the Runes in the correct order.

• You can check the Rune FAQ for further help.

Runewords with Io

Runeword	Stats	Comments	Active In
			1.11	1.10	1.09
Black ThulIoNef Thul (10) + Io (16) + Nef (4) Clubs, hammers, maces Clvl Required: 35	+120% Enhanced Damage +200 to Attack Rating +3-14 Cold Damage (3 sec) 15% Increased Attack Speed Knockback 12 Level 4 Corpse Explosion Charges 40% Chance of Crushing Blow -2 Magic Damage +10 to Vitality	See it here.	Yes	Yes	Yes
Delirium LemIstIo Lem (20) + Ist (24) + Io (16) Armor Clvl Required:	1% Chance To Cast lvl 50 Delirium When Struck 10% Chance To Cast lvl 14 Mind Blast When Struck 20% Chance To Cast lvl 13 Terror When Struck 33% Chance To Cast lvl 18 Confuse On Striking +2 To All Skills +261 Defense +10 To Vitality 50% Extra Gold From Monsters 25% Better Chance of Getting Magic Items Level 17 Attract (60 Charges)	See it here. See it in action here.	Yes	Yes	No
Dream IoJahPul Io (16) + Jah (31) + Pul (21) Helms & Shields Clvl Required	10% Chance To Cast Level 15 Confuse When Struck Level 15 Holy Shock Aura When Equipped +20-30% Faster Hit Recovery (varies) +30% Enhanced Defense +150-220 Defense (varies) +10 To Vitality Increase Maximum Life 5% (Helms Only) +50 To Life (Shields Only) +0.625-61.875 To Mana (Based On Character Level) All Resistances +5-20 (varies) 12-25% Better Chance of Getting Magic Items (varies)	Ladder Only	Yes	Yes	No
Memory LumIoSolEth Lum (17) + Io (16) + Sol (12) + Eth (5) Staves (Not Orbs). Clvl Required: 37	Lowers Target's Defense by 25% 33% Faster Cast Rate +3 Sorceress Skill Levels +50% Enhanced Defense -7 Magic Damage +20% Max Mana +9 Minimum Damage +10 Energy +10 Vitality +2 Static Field +2 Energy Shield	See it here.	Yes	Yes	Yes
Pride ChamSurIoLo Cham (32) + Sur (29) + Io (16) + Lo (28) Polearms Clvl Required:	25% Chance To Cast Level 17 Fire Wall When Struck Level 16-20 Concentration Aura When Equipped (varies) 260-300% Bonus To Attack Rating (varies) +1-99% Damage To Demons (Based on Character Level) Adds 50-280 Lightning Damage 20% Deadly Strike Hit Blinds Target Freezes Target +3 +10 To Vitality Replenish Life +8 1.875-185.625% Extra Gold From Monsters (Based on Character Level)	Ladder Only	Yes	Yes	No
White DolIo Dol (14) + Io (16) Wands Clvl Required: 35	Hit causes monster to flee 25% 20% Faster Cast Rate Magic Damage Reduced by 4 +13 to mana +10 to vitality +3 to bone and poison skills +4 to skeleton mastery +2 to bone spear +3 to bone armor	See it here.	Yes	Yes	Yes